Employing multi-omics data to improve childhood growth outcomes

Small-quantity lipid nutrient supplements (sq-LNS)–along with environmental interventions (e.g., water treatment, sanitation, and handwashing)–are utilized to prevent chronic malnutrition and subsequent stunted growth. However, these interventions only address a fraction of the growth deficit children are facing. Our project utilizes microbiome and metabolomics data from the WASH Benefits Bangladesh trial to determine what host and microbial factors might be contributing to reduced absorption and usage of sq-LNS. We hope this work will help improve preventative and therapeutic responses to stunting.